Assume that the metabolism of glucose to pyruvate does not

Assignment Help Mechanical Engineering

Reference no: EM13633092

Glycolysis can be simplified as:

Glucose + 2Pi + 2ADP + 2NAD+ -> 2 pyruvate + 2ATP + 2NADH + 2H+ + 2H2O

a) Calculate the standard, biochemical Gibb's free energy of this reaction.

b) How much energy (work) is lost to irreversibilities in this process?

Hint: remember that DG = DH - T0Sgen

c) Assume that the metabolism of glucose to pyruvate does not generate ATP. How much useable energy (heat) is generated?

Hint: use the following reaction

Glucose + 2NAD+ -> 2 pyruvate + 2NADH + 2H+ + 2H2O

d) Using you answer from part c), calculate the maximum amount of ATP that could be generated.

Hint: ATP generation is ADP + Pi -> ATP + H2O

e) What is the efficiency of glycolysis in generating ATP (actual ATP generated over reversibly generated ATP)?

Reference no: EM13633092

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