Assume n-butylmalonate is added to an aerobic

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Q. The transport system that conveys malate and α-ketoglutarate across the inner mitochondrial membrane is inhibited by n-butylmalonate. Assume n-butylmalonate is added to an aerobic suspension of kidney cells using glucose exclusively as fuel. Predict, with description, the effect of this inhibitor on

(A) glycolysis,

(B) Oxygen consumption,

(C) Lactate formation, and

(D) ATP synthesis

Reference no: EM135556

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