Assessment of bone mineral density and vitamin D status

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Reference no: EM132176893 , Length: word count:2500

Assignment -

Research Protocol Title: Assessment of bone mineral density, vitamin D status and calcium intakes in ileostomy patients.

PROJECT DETAILS -

Background - Neuropsychiatric disorders are among the leading cause of ill-health and disability worldwide affecting approximately 450million. Dementia, depression and anxiety are common in older age. B-vitamins are involved in one carbon metabolism and are important for the functioning of the central nervous system. There is emerging evidence to suggest that B-vitamin status plays an important role in the maintenance of brain health in ageing. However the majority of evidence to date has focused on plasma homocysteine and folate and few studies have considered the role of all the relevant B-vitamins in this.

Aims - The aim of this study is to determine if low B-vitamin status (i.e. folate, vitamin B12, vitamin B6 and riboflavin) is associated with mental health in older people, with a particular focus on cognitive dysfunction, depression and anxiety.

Lay summary - Describe your proposed research in a way that will be clear to members the public who do not have a grasp of medical or scientific terminology.

PROPOSED INVESTIGATION -

To include background, hypothesis, project aims, proposed methods (including statistical approaches and power calculation), a project timeline (e.g. Gantt chart) and references. Expand this section as necessary to include all required information. Take note of individual word counts specified throughout.

Project aims - The primary aim of this study is to determine if B-vitamin status is associated with mental health in older people from the TUDA aging cohort study.

Specific aims are to:

determine if a suboptimal B-vitamin status in older Irish adults can lead to cognitive dysfunction including dementia;
determine if a suboptimal B-vitamin status in older Irish adults can lead to the development of depression;
determine if a suboptimal B-vitamin status in older Irish adults can lead to the development of anxiety disorders;
investigate the influence of fortified food consumption on mental health; and
investigate the influence of B-vitamin supplement use on neuropsychiatric performance.

Attachment:- Assignment Files.rar

Reference no: EM132176893

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Assessment of bone mineral density and vitamin D status : Research Protocol Title: Assessment of bone mineral density, vitamin D status and calcium intakes in ileostomy patients

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