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In 1999, scientists reported that a particular variant of theangiotensin-converting enzyme (ACE) gene was associated withsuperior physical endurance. The variant, known as the ACEinsertion polymorphism, was found to be present in a higherproportion of elite endurance athletes, especially long distancerunners, than in the general population.
Vignette:
Marathon University is offering full-tuition scholarships and aguaranteed spot on the varsity track team to high-school sophomoreswho "pass" a genetic test. If the parents sign a consent form,University doctors will screen them for the ACE insertionpolymorphism.
Discussion points:1 Is it likely that a single gene determines physical endurance?2 Are other genes likely to be important?3 What other factors determine whether a child will grow up to bean elite endurance athlete?4 Should parents be allowed to use genetic information to make decisions that will limit their children's choices in adulthood?5 What else should MU do if it is concerned about the well being ofthe future student-athlete?
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