Are animal models necessary for human biomedical research

Reference no: EM133414449

Questions:

1. What information and ingredients are needed to attempt gene therapy of an inherited disease?

2. Are animal models necessary for human biomedical research? Justify your statement.

3. What did researchers learn about gene therapy of the RPE65 mutation in briard dogs that was important for treatment of humans with LCA2?

4. The gene that is mutated in cystic fibrosis patients was identified in 1989. As of today, there is no gene therapy for this disease. Why were researchers so confident about curing the disease in the 1990s?

5. Gene transfer was established in animals in the early 1980s, but the first approved human gene therapies did not occur for more than 30 years. Why did the application of basic knowledge about genes to human therapy take so long?

Reference no: EM133414449

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