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Aqueous solubility in stomach environment

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Question 1.

A drug with a basic functional group with a pKa=22 will have high aqueous solubility in the stomach environment.

True False

Question 2

Cannabinoid receptors, CBI, are responsible for appetite control. The binding of their endogenous ligands causes the increase in appetite. A new drug candidate targeting CBI reduces appetite and helps promote weight loss in patients in clinical trials. What kind of mechanism is likely associated with this new drug candidate?

Reference no: EM133425476

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