Appropriate vesicles and their target membranes

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SNAREs exist as complementary partners that carry out membrane fusions between appropriate vesicles and their target membranes. In this way, a vesicle with a particular variety of v-SNARE will fuse only with a membrane that carries the complementary t-SNARE. In some instances, however, fusions of identical membranes (homotypic fusions) are known to occur. For example, when a yeast cell forms a bud, vesicles derived from the mother cell’s vacuole move into the bud where they fuse with one another to form a new vacuole. These vesicles carry both v-SNAREs and t-SNAREs. Are both types of SNARE essential for this homotypic fusion event?

Reference no: EM13528188

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