Appropriate method for assessing the risk of cystic fibrosis

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A 28-year-old woman and a 25-year-old man present for genetic counseling. Both are white and have one sibling affected with cystic fibrosis. Which of the following is the most appropriate method for assessing the risk of cystic fibrosis transmission to the child?

(A) Biochemical testing

(B) Fluorescence in situ hybridization (FISH)

(C) Karyotype analysis

(D) Polymerase chain reaction (PCR)

(E) Western blot analysis

Reference no: EM132510163

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