Appropriate cut-off level for an abnormal test

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In an alcoholic hepatitis-screening program, researchers are discussing the appropriate cut-off level for an abnormal test. One researcher argues for a cut-off value of 50 IU/ml while another argues for a cut-off value of 80 IU/ml. A higher value in IU/ml indicates a higher severity of the disease. Select the correct answer from the options below:

A) The sensitivity and specificity are the same for both the cut-off values

B) The number of false negatives is higher with a cut-off of 50 IU/ml

C) The number of false positives is lower when the cut-off or threshold is 50 IU/ml

D) The sensitivity with a 50 IU/ml threshold is greater with a cut-off of 80 IU/ml

Reference no: EM131839531

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