Reference no: EM131875486

Question:

Background and Significance Sections of the Grant Proposal

For this week's assignment, you will complete the Background (including a literature review) and Significance sections of your grant proposal following the Grant Proposal Guidelines.

See the Sample Grant Proposal Template as an example and use it as a template for your Grant Proposal. The more complete your assignment is, the more feedback you will receive for the Final Project.

In addition, you will create the References page for your proposal by taking the sources from your Week Two annotated bibliography and converting them into a standard APA-formatted References list. Be sure to include at least five more peer-reviewed sources on your References page (so that you have at least 15 sources as required for the Final Project).

You will conduct a search in the Ashford University Library and/or on PubMedCentral. to locate at least 10 scholarly peer-reviewed articles that are relevant and that support your funding request. Create your preliminary annotated bibliography and ensure that your resources are relevant and supportive of the Specific Aims as well as the Background and Significance sections of your grant proposal (the Background and Significance sections will be written in Week Three).

Compose the Specific Aims section following the Grant Proposal Guidelines. See the Sample Grant Proposal Template. as an example and use it as a template for your Grant Proposal. The assignment should be one page, excluding the bibliography.

Carefully review the Grading Rubric. for the criteria that will be used to evaluate your assignment.

Title- Applications of CRISPR/Cas9 for Gene Editing in Mutant Huntingtin Gene In Vitro

Grant Proposal - Topic, Specific Aims and Bibliography

For this assignment, you will select a topic for your grant proposal (i.e., Final Project due in Week Six). Then you will write the Specific Aims section and create a preliminary bibliography.

Grant Proposal Guidelines - Final Project

Instructions: This assignment involves preparing a grant proposal requesting support for a 12-month research project. The total amount of support you may request is $60,000 (including direct and indirect costs). You will choose a specific topic in neuroscience or neuropsychology and develop a grant proposal based on a review of the literature and identification of a research hypothesis. The grant proposal must be six to eight double-spaced pages in length (not including title page, references list, and appendix), 12point font, and formatted according to APA style as outlined in the Ashford Writing Center. You must use at least 15 peer-reviewed sources in addition to the text. The components of your proposal are outlined below. View the Sample Grant Proposal to see an example of a completed proposal in APA format. Use the Grant Proposal Template to create your grant proposal. NOTE: All titles should be centered and all content should be formatted as in the Grant Proposal Template and the Sample Grant Proposal, not as outlined below in this guidelines document.

Title Page (1 page):
- Title of your grant proposal
- Your full name
- Course name and number
- Instructor's name
- Date submitted

Specific Aims: (1 page) Clearly and concisely state the goals of your grant proposal. Summarize the Specific Aims: (1 page) Clearly and concisely state the goals of your grant proposal. Summarize the expected outcome(s), including the impact that the results of the proposed research will exert on the research field(s) involved. List the specific objectives of your grant proposal (e.g., to test a stated hypothesis, create a novel design, solve a specific problem, challenge an existing paradigm or clinical practice, address a critical barrier to progress in the field, or develop new technology).

Background: (6 - 8 pages for Background, Significance, Proposed Study, and Budget Justification sections) The goal of this section is to provide a well-developed literature review that provides the basis for the research problem and illustrates to the reader that you are knowledgeable about the scope of the theory. Research as many studies pertaining to the theory as possible, and summarize them in a succinct manner. In most respects, this section is precisely what you do when you write the introduction section to a research paper. Your background section should clearly state the rationale for the topic you have chosen. It includes the literature review you conducted to identify an area of neuroscience or neuropsychology that has not yet been studied. At the end of this section, you should clearly specify your research hypotheses.

Significance: Explain the importance of the problem or critical barriers to progress in the field that the proposed project addresses. Explain how the proposed project will improve scientific knowledge, technical capability, and/or clinical practice in one or more broad fields. Describe how the concepts, methods, technologies, treatments, services, or preventative interventions that drive this field will be changed if the proposed aims are achieved.

You will conduct a search in the Ashford University Library and/or on PubMedCentral. to locate at least 10 scholarly peer-reviewed articles that are relevant and that support your funding request.

Create your preliminary annotated bibliography and ensure that your resources are relevant and supportive of the Specific Aims as well as the Background and Significance sections of your grant proposal (the Background and Significance sections will be written in Week Three).

See a sample annotated bibliography

Compose the Specific Aims section following the Grant Proposal Guidelines. See the Sample Grant Proposal Template as an example and use it as a template for your Grant Proposal. The assignment should be one page, excluding the bibliography.

Attachment:- Sample template.rar