Analyse the properties of the protein

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Reference no: EM133291158

Question: Holien-X has re-analysed their data using network-based methods and discovered new information which shows that Aurora Kinase B (Uniprot code: Q96GD4) is the best druggable option as it is:

• highly expressed and upregulated in the diseased patients compared to controls

• has close homology to mouse

• has a close homolog to construct a high quality homology model

• has a known role in cancer

Your job is to download the alphafold homology model and confirm its suitability for a drug discovery campaign. For example, you may like to; analyse the quality of this model, analyse the properties of the protein, search for druggable pockets etc. Write these details into your report with figures to guide the team at Holien-X

Reference no: EM133291158

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