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Alternative methods of treating parkinson disease

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Two different groups of researchers are studying alternative methods of treating Parkinson's disease. 

Group A - is working with black widow spiders. They have determined that their venom stimulates synaptic vesicles in the presynaptic membrane to release neurotransmitters into the synapse. The researchers have isolated an enzyme that behaves like the venom. in the synapse. 

Group B -  is working with mushrooms. They have isolated a molecule in these mushrooms that is similar in structure to dopamine. The molecule attaches to the dopamine receptor sites on the postsynaptic membrane. 

You are a member of the Natural Sciences and Engineering Research Council of Canada (NSERC). You must decide which of the two groups of researchers can obtain the grant for Parkinson's disease research.

  1. Which of the two groups of researchers should receive the grant money?
  2. Explain your decision by explaining the mechanism of both substances.
  3. Describe the action of the spider venom and explain why it is or is not useful to treat Parkinson's disease.
  4. Describe the action of the mushroom molecule and explain why it is or is not useful to treat Parkinson's disease.

Reference no: EM132745190

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