Alteration of bacterial cell osmotic equilibrium

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"The bactericidal effect of CHG is a result of the binding of the CHG cationic molecules to negatively charged bacterial cell walls and extramicrobial complexes. At low concentrations, CHG causes an alteration of bacterial cell osmotic equilibrium, resulting in leakage of potassium and phosphorus, and inhibits growth (ie, it is bacteriostatic). At high concentrations, CHG produces a rapid bactericidal effect by causing the cytoplasmic contents of the bacterial cell to precipitate, resulting in cell death".

Reference no: EM131720410

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