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Explain in simpler terms"Adverse effects and interactions. The major adverse effect is cardiotoxicity (dysrhythmias). Risk is increased by hypokalemia, which can result from concurrent therapy with diuretics (thiazides and loop diuretics). Accordingly, it is essential that potassium levels be kept within the normal range (3.5 to 5 mEq/L). The most common adverse effects are GI disturbances (anorexia, nausea, vomiting, abdominal discomfort). CNS responses (fatigue, visual disturbances) are also relatively common. Antidysrhythmic uses. Digoxin is used only for supraventricular dysrhythmias. The drug is inactive against ventricular dysrhythmias.
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