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A projectof the effect of surgical repair or reconstruction on the function of the hip labrum is critical to the advancement of hippreservation surgery; however, validated models of the hip that allow the quantification of labral function in functional joint positions have yet to be developed. PURPOSE:To evaluate (1) whether intra-articular pressures within the hip are regulated by fluid transport between the labrum and femoral head and (2) whether the sealing capacity of the labrum varies with joint posture. STUDY DESIGN:Descriptive laboratory study. METHODS:The sealing ability of the hip labrum was measured during fluid infusion into the central compartments of 8 cadaveric specimens. Additionally, the pathway of fluid transfer from the central to the peripheral compartment was assessed via direct visualization in 3 specimens. The effect of joint posture on the sealing capacity of the labrum was determined by placing all 8 specimens in 10 functional postures. The relationship between pressure resistance and 3-dimensional motion of the femoral head within the acetabulum was quantified using motion analysis and computer modeling. RESULTS:Resistance to fluid transport from the central compartment of the hip was directly controlled by the labrum during loading. Maximum pressure resistance was affected by joint posture (P = .001). Specifically, positions that increased external rotation of the joint (pivoting) provided an improved seal, while positions that increased flexion combined with internal rotation (stooping) augmented the ease of fluid transport from the central to the peripheral compartment. Maximum pressure resistance was associated with the distance between the labrum and femoral head during pivoting. CONCLUSION:This study demonstrated that the transfer of fluid from the central compartment of the hip occurs at the junction of the labrum and femoral head. Joint position was shown to strongly affect the sealing function of the labrum and was attributable to the distance between the labrumand femoral head in certain positions. CLINICAL RELEVANCE: Altering the relationship between the labrum and femoral head may disrupt the sealing ability of the labrum, potentially leaving the joint at risk for pathological changes with time.
Explain the study of the hypothesis? State the outcome variables and how were they determined?
Determine the significance of the observation that knocking out MyD88 abrogates increases in Factor B and C3a but knocking out of TRIF does not ? Describe in molecular terms.
evaluate and contrast the electron transport systems. Include a discussion of the inputs and outputs of each ETS and also give examples of specific electron carriers.
When the differential is obtained what is the meaning of the percentage of.define What are the clinical scenarios.
Describing how you would test the hypothesis. Start by examining the living species around you. Ever wonder why the pollinator is attracted to the particular flower.
The digastric and omohyoid muscles are similar in that they both have________. Suprahyoid, Two bellies, 60
How various molecules of ATP are USED UP in the glycolysis pathway.
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Within the two groups define by the bone mass, smaller skeletons have bones with evidence of epiphyseal plates, but larger bones have only a thin line where the epiphyseal plates should be. Give the age group and gender of the individuals in this fin..
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A gerbil poplulation has one hundred light blue gerbiles, 250 dark blue gerbils, and 150 black gerbils. In one generation 10 percent of the home population is displaced by a gang of tough light blue gerbils.
The delta G for hydrolysis of the amide group from glutamine is -14.2 kJ/mol at 25C. Compute the keq' for this hydrolysis.
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