Adrenergic receptor antagonists to control blood pressure

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Sally and Rose are identical twins who weigh the same. They are both taking beta-adrenergic receptor antagonists to control blood pressure. Sally is taking propranolol and Rose is taking carvedilol. They are each taking an equally therapeutic dose of their respective drug. Rose is having more episodes of orthostatic hypotension. Why is Rose having more trouble with orthostatic hypotension?

A Carvedilol is a third generation beta adrenergic antagonist with vasodilating actions.

B The bioavailability of carvedilol is similar to the bioavailability of propranolol.

C The halt-life of propranolol is longer than the half-life of carvedilol.

D Propranolol is a cardio selective adrenergic antagonist whereas carvedilol is not.

Reference no: EM133274133

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