Activation of the macrophage

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Question: After phagocytosis of a pathogen, the phagosome becomes very acidic with the pH dropping to between 3.5 and4. However, some of the enzymes are important to kill pathogens only work when the pH is higher than 5.

How does activation of the macrophage make it possible for those enzymes to function?

 

Reference no: EM1392187

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