Solution-Acidic pka values of the respective hydroxyl

Acidic pka values of the respective hydroxyl products

Assignment Help Chemistry

Reference no: EM13279880

Assignment One:

Heroin is 3, 6-diacetylmorphine. Heroin is 2-3 times more potent than morphine.

In vitro and in vivo, to which product does heroin hydrolyze first, (3- or 6-acetylmorphine), and why?

Hint:What are the acidic pKa values of the respective hydroxyl products? Look up the structures on the internet or use the UF library online e-journals.

Assignment Two:

Acetyl sulfisoxazole, is readily hydrolyzed in vivo to sulfisoxazole. On the other hand, the acyl group in amikacin, is stable to hydrolysis in vivo. Both acetylsulfisoxazole and amikacin are acyl derivatives where the acyl group is attached to nitrogen.
Why is one stable and the other not?

Hint:What are the acidic pKa values of the respective N-H groups formed on hydrolysis. Look up the structures on the internet or use the UF library online e-journals.

Reference no: EM13279880

Questions Cloud

Explain chemical reagents commonly found in a chemical : From the understanding of colligative properties, how would I design an experiment to measure the freezing point of a material which freezed at -2'c using the same apparatus used in the laboratory and any chemical reagents commonly found in a chem..

Determine density of mobile charge at semiconductor surface : The silicon substrate is N-type (doping level ND = 7x10^16cm-3), and the gate is heavily doped N+-type polysilicon. Assuming zero oxide charge density, determine the density of mobile charge at the semiconductor surface, if the voltage applied bet..

What is its output voltage : A Hall probe uses the Hall effect to measure the size of magnetic fields - it does this by measuring the potential difference across the electric field created by the displacement of charge

Find the radius of the turn : A car of mass M = 900kg traveling at 50.0km/hour enters a banked turn covered with ice. What is the radius r of the turn

Acidic pka values of the respective hydroxyl products : What are the acidic pKa values of the respective hydroxyl products? Look up the structures on the internet or use the UF library online e-journals.

Define molecular weight of p-dichlorobenzene : what would be the effect on my calculated molecular weight of p-dichlorobenzene if my lab partner left the stopper off of the apparatus while I was weighing the solid p-chlorobenzene. Explain in detail what would happen if this occured and how it ..

Find the impulse response h of the average : Where x(t) is the input and y(t) is the output. a.] Find the impulse response h(t) of the average. Is the system causal b.] Let x(t) = u(t). Find the output of the average.

Calculate the effect of it on the reaction conversion : Consider the ammonia reaction at 100F and 3600psi absolute pressure where nitrogen and hydrogen are the reactants. Gibbs free energy of formation for ammonia is -3.9 kcal/gmole and the standard heat of formation for ammonia is -10.96 kcal/gmole. Find..

How long does it take for the grinding wheel to stop : An electric motor rotating a workshop grinding wheel at a rate of 9.20x101 rev/min is switched off. How long does it take for the grinding wheel to stop

User Account

All Pages

Acidic pka values of the respective hydroxyl products

Reference no: EM13279880

Reference no: EM13279880

Questions Cloud

Reviews

Write a Review

Chemistry Questions & Answers

Steps in the mechanism for the following reaction

Prior to placing piece of metal into the graduated cylinder

Write the structures of the saytzeff elimination

Calculate ph - chemistry questions

How many mols of hydrogen can produce

Analysis of corrosion mechanisms

Chemical and pharmaceutical science

Calculate the approximate sulphur

What is the structure - stereochemistry

Design a qualitative analysis scheme

What will be the resultant pressure

The 1h nmr spectrum

Assured A++ Grade

Academics

Major Subjects

Majors

Get In Touch

TERMS & POLICIES

HELP & SUPPORT