Acetylcholine from accumulating in neuromuscular junction

Assignment Help Biology

Reference no: EM1394881

1. As a Nursing student in Advanced Human Anatomy, you were able to observe a total hip replacement. While the O.R. personnel where prepping the patient for the surgical procedure, the anesthesiologist assumed (rightly so!) that you had some physiology background. As such, she launched into the following procedural explanation: The patient will need to be intubated, therefore he will be given a single dose of the neuromuscular blocking agent, succinylcholine to provide muscular relaxation during the surgery and to facilitate the insertion of the endotracheal tube. The anesthesiologist asked you the following:

a) Beginning with depolarization at the neuromuscular junction, describe the normal sequence of events which lead to muscle contraction. (10)

b) What prevents acetylcholine (ACh) from accumulating in the neuromuscular junction and causing a sustained contraction in a normal individual? (3)

c) Succinylcholine acts as a depolarizing agent that prevents repolarization of the nerve. Therefore, no further ACh is released until the drug is cleared. Name another site within the neuromuscular junction that might be affected to prevent muscle contraction. (Hint: curare acts by this mechanism) (2)

Reference no: EM1394881

Questions Cloud

Draw the metabolic pathways for glycolysis : Draw the metabolic pathways for Glycolysis, the Krebs cycle, and the electron transport chain. Indicate at the right the total number of ATP and NADH produced or consumed.

Negative sales using multiple regression analysis : If sales is the variable you are trying to explain and you have 2 independent variables of color and price. The color coefficient is 100, and the price coefficient is -200. You have an intercept coefficient of 999 and an r-squared value of .2706. ..

Calculate what value of the oil viscosity : Determine the numbers of moles of S8 that are required to make 0.600 moles of SF4.

Is it better suited to disseminate information : Explaining which of the two approaches (scholarly or popular media) is better suited to disseminate information about your selected topic

Acetylcholine from accumulating in neuromuscular junction : As a Nursing student in Advanced Human Anatomy, you were able to observe a total hip replacement. While the O.R. personnel where prepping the patient for the surgical procedure.

Which one is oxidized by using oxidation number concept : N2O4(g) + KCl(s) → NOCl(g) + KNO3(s) Find out oxidation number of each and find which one is reduced and which one is oxidized by Using oxidation number concept? Also write net ionic equation and ionic equation.

Employee satisfaction survey : You're designing a survey to assess employee satisfaction. Provide a question that will produce: Develop five demographic questions to measure gender, age, years of experience, level of education, and ethnicity.

What is the linear correlation coefficient : A data set of ordered pairs with a negative linear correlation has a coefficient of determination of 85.2%. What is the linear correlation coefficient?

Find out the required pressure to compress : Find out the required pressure to compress 180 liters of N at 1.0 atm into a tank whose volume is 34 liters.

User Account

All Pages