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A young man was brought to the hospital suffering an unknown disease. Unfortunately, the young patient did not make it. Upon examination of his liver cells it was determined that the liver cells were extremely unhealthy. In fact, it was determined that there was an accumulation of a protein (called Y) that was supposed to be secreted from the cell, in the ER. Very little if any of protein Y was secreted from the liver cells. The accumulation of protein Y in the ER had appeared to cause these cells to undergo apoptosis. What might you surmise about protein Y in the patient based on our discussions in class? Can you make a hypothesis for what you think is happening? How would you test that hypothesis? What would the results look like and how would you interpret those results?
Assume y ou are analyzing a dominant allele in fruit flies that mutates to a recessive allele at the relatively high rate of 10 -6 per generation.
Assume you review a young patient in the emergency room who is complaining of ankle pain following a soccer game. The patient shows to you that an accident resulted in his foot being forced into an excessively inverted position.
From the list given below what options applies to fibrous proteins. Monomers are held together by covalent glycosidic linkages.
Swelling of the abdomen and legs due to edema is characteristic of starving children with kwashiorkor, protein-deficiency disorder. What is the relationship between this symptom and procedure of capillary exchange.
What disorder does this man have? Gastric secretions normally include about 10mmole/L potassium. How do you account for the low serum potassium in this patient.
A seventy-five year-old woman with congestive heart failure complains that her condition gets worse when she worries and is under a lot of stress.
Starting with a hydrophilic signaling molecule, explain the process that takes place with a G-coupled protein signaling pathway. Suppose that cAMP is your main secondary messenger.
1000 molecules are bouncing at 300K in two wells separated by a free energy gap DG = 6·10-21 J. Compute how many particles on average are in each well.
Compare the effects of this mutation with the effects of cholera toxin.why G-protein linked receptors activate G proteins.
Clostridium and Streptococcus are both catalase-negative. Streptococcus grows by fermentation. Why is Clostridium killed by oxygen, whereas Streptococcus is not.
When Mexican hairless dogs are crosses with normally haired dogs, about half the pups are hairless and half have hair. When, however, two Mexican hairless dogs are mated, about a third of the pups produced have hair, about two thirds are hairless, an..
Which distributed database process is best under these circumstances. How is the replication of the viral genome of retroviruses unique among the viruses? Why was it before believed that only DNA viruses could cause cancer.
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