A plasma cortisol determination indicated a low cortisol

Assignment Help Biology
Reference no: EM13929801

Endocrinology(Addison's Disease)

A 45-year-old male from the Midwest presented with the following symptoms during February: weakness, fatigue, orthostatic hypotension, weight loss, dehydration, and decreased cold tolerance. His blood chemistry values follow:

   Serum sodium 128 mEq/L

   Serum potassium 6.3 mEq/L

   Fasting blood glucose 65 mg/dL

   Serum creatinine 0.5 mg/dL

Hematology tests resulted in the following values: Hematocrit 50%; Leukocytes 5000/cu mm

patient also noticed increased pigmentation (tanning) of both exposed and nonexposed portions of the body and back. A plasma cortisol determination indicated a low cortisol level. Following administration of ACTH, plasma cortisol did not rise significantly after sixty and ninety minutes. Endogenous circulating levels of ACTH were later determined to be significantly elevated.

1. What endocrine organ is the site of the malfunction? . Is this a primary or secondary disturbance?

2. What is the name of this disorder?

3. Discuss the electrolyte (Na+ and K+) disturbances resulting from this disorder. Which hormone is involved and are the levels of this hormone abnormally high or abnormally low?

4. Discuss the metabolic disturbances resulting from this disorder. Which hormone is responsible?

5. What is the cause of tanning in this patient?

6. What type of replacement therapy would be required for this patient?

7. Diagram the feedback loop for this endocrine disorder.

8. What is the long-term outlook for? Might one expect the abnormal pigmentation to resolve? Explain.

*I just need help on the last question(#8). Thanks.

Reference no: EM13929801

Questions Cloud

In the spot exchange market : Six-month T-bills have a nominal rate of 5%, while default-free Japanese bonds that mature in 6 months have a nominal rate of 3%. In the spot exchange market, 1 yen equals $0.01. If interest rate parity holds, what is the 6-month forward exchange rat..
Calculate the sustainable growth : Calculate the sustainable growth based on the following information: D= 30% and ROE = 25%
Create a form using a master detail relationship : Select the form and switch between the views (Forms, Layout, and Design) to change the properties or the form's appearance as desired.
Attempted to collect an account and, when unsuccessful : In the cash flow column, indicate whether the item is an operating activity (OA), investing activity (IA), or financing activity(FA).
A plasma cortisol determination indicated a low cortisol : Patient also noticed increased pigmentation (tanning) of both exposed and nonexposed portions of the body and back. A plasma cortisol determination indicated a low cortisol level. Following administration of ACTH, plasma cortisol did not rise signifi..
Results of exchange rate changes : Early in September 1983, it took 275 Japanese yen to equal $1. Nearly 28 years later, in August 2011, that exchange rate had fallen to 105 yen to $1. What would the dollar price of the automobile be in August 2011, again assuming that the car's price..
Define ethical behavior based upon the context : Moral Relativism refers to being able to define ethical behavior based upon the context. Which do you agree with as a basis for ethical action and why?
Operating section of the cash flow statement : The income statement and the operating section of the cash flow statement present a company’s results in very different formats. In your opinion, which statement is more important to shareholders? To company management?
What debt and equity mix is the best mix and why : Independent of item 4, your company needs to raise capital to build an addition. The addition is 5% of your current total assets. What debt/equity mix is the best mix and why?  how long will it take for the project to be accepted?

Reviews

Write a Review

Biology Questions & Answers

  Premature termination of transcription

Assume the two tryptophan codons within the leader peptide of the trp operon were changed from tryptophan to asparagine.

  Why is the l-enantiomers used for all biological amino acids

Why is the L-enantiomers used for all biological amino acids? Find 3 different reasonable theories or hypotheses.

  Discussion board db is part of the core of online learning

discussion board db is part of the core of online learning. classroom discussion in an online environment requires the

  Homologous-vestigial-analogous-radiative adaptation

What were the main conclusions of Darwin's five year voyage around the world? Feel free to use words like homologous, vestigial, analogous,radiative adaptation etc

  What are the probable genotypes of all the parents

What are the probable genotypes of all the parents.  What specific benefits will cellular organelles have if enclosed by a cell membrane alike to the plasma membrane.

  Color blindness is sex-linked trait-heterozygous brown-eyed

A heterozygous brown-eyed human female who is a carrier of color blindness marries a blue-eyed male who is not color-blind. Color blindness is a sex-linked trait. Assume that eye color is an autosomal trait and that brown is dominant over blue. Wh..

  How can a percent be changed to a decimal

How can a percent be changed to a decimal and Distinguish between Roman numerals and the Arabic numeral system. Why must health care workers be familiar with Roman numerals

  How lipoproteins are secreted to the outer membrane

Describe in detail the two hypothesis for LPS movement to the outer membrane. Compare and contrast in detail secretion of outer membrane lipoproteins and LPS.

  When looking at the current clades of animal phylogeny

When looking at the current clades of animal phylogeny, what are the key steps in animal evolution that have occured from the common ancestor of all animals? briefly explain why these are significant

  What is hemophilia

What is hemophilia and why can females, but not males, be carriers of hemophilia and other X-linked recessive characteristics?

  How do cadherins, igsf members differ at the molecular

How do cadherins, IgSF members, and selectins differ at the molecular level in the way they mediate cell-cell adhesion?

  Classify as appetitive or consummatory behaviors

Examine an animal that you can spend some time observing for at least 10 minutes. Prepare a brief ethogram (five behaviors at most), and classify them as appetitive or consummatory behaviors.

Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd