A liquid samples either damage the column or the hplc system

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Some liquid samples cannot be injected directly into an HPLC system because they could either damage the column or the HPLC system. For these samples, solid phase extraction (SPE) is used prior to analysis. Explain SPE? ( I have som eideas, but having a hard time keeping it short and to the point)

Reference no: EM13522879

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