Mutation :
A mutation is a chemical or physical change that alters the sequence of bases in DNA molecule. Anything that causes mutation is called mutagen. A mutation results from ultraviolet light, ionisation radiations, chemicals or viruses. The changes in sequence of bases in DNA are repaired by special enzymes in the cell. If it is not, the protein produced has no biological activity and the cell dies.
These mutations often prove harmful and give rise to symptoms that cause diseases. Sickle-cell anaemia is one such example. Such disease is passed on from one generation to the next generation.
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