Chemical properties of Acid Amides Assignment Help

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Chemical properties

         (i) Hydrolysis     

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         (ii)           Amphoteric nature (Salt formation)

         It shows feebly acidic as well as basic nature.

         440_chemical properties of acid amide1.png

         (iii) Reduction     1868_chemical properties of acid amide2.png

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         (iv) Dehydration

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         (v) Reaction with nitrous acid

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         (vi) Hofmann bromamide reaction or Hofmann degradation : This is an important reaction for reducing a carbon atom from a compound, i.e.,-CO NH2 is changed to -NH2 group.

         2342_chemical properties of acid amide6.png

  •        In this reaction a value of intermediates have been isolated; N-bromamides, RCONHBr; salts of these bromamides [RCONBr-]K+ ; Isocyanates, RNCO.
  •       Nitrene rearranges to form isocyanate.

         (vii) Reaction with grignard reagent

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