Antimicrobials: These are the chemical substances used to cure infections due to micro-organisms. These are also named microbes. Any creature which causes disease is named pathogen.
The control of microbial diseases may be get by the following three types,
(i) By drugs which kill the creature in the body (bactericidal).
(ii) By drugs which arrest or inhibit the growth of the organism (bacteriostatic) and
(iii) By increasing immunity and resistance to infection of the body (immunity).
Antimicrobial matters can be synthetic chemicals like sulphonamides, paraamino salicylic acid or they may be antibiotics like tetracycline, penicillin, chloramphenicol, etc.
The common example of antimicrobial drug is sulphanilamides which are effective in wide range of micro-organisms. These are structural analogues of p-amino benzoic acid.
Large quantity of derivatives of sulphanilamide such as sulphadiazine, sulphadimidine, sulphadimethoxine, sulphadoxine, sulphasomidine are being used as anti-microbials.
Sulphonamides in mixture with trimethoprim are preferred in the treatment of infections of urinary tract.
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