Alkyl Cyanides
(i) Methods of preparation
(a) From alkyl halides : The disadvantage of this method is that a mixture of nitrile and isonitrile is formed.
(b) From acid amides :
Industrially, alkyl cyanides are formed by passing a mixture of carboxylic acid and ammonia over alumina at 500°C.
(c) From Grignard reagent
(d) From primary amines : Primary amines are dehydrogenated at high temperature to form alkyl cyanides. This is also a commercial method.
(e) From oximes :
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